Lupa Project

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History

Jan 2008, as a collaborative European research project between 20 veterinary schools in 12 European countries.

Aims

Based on the premise that humans and dogs live in the same environment and suffer from the same diseases, and can therefore aid understanding of the genetic origin of disease: identify the genes in canines which are implied in disease development in order to improve understanding of the mechanisms and pathways of pathology, thus, ultimately benefiting human medicine.

Available with paid subscription only.

Activities

Members collect DNA samples from large cohorts of dogs suffering from a range of thoroughly defined diseases of relevance to human health. Once the cohorts are built, DNA samples are sent to a centralized, high-throughput SNP genotyping facility. The SNP genotypes are stored in a central database and made available to participating collaborating centres, who analyse the data with the support of dedicated statistical genetics platforms. Following genome wide association and fine-mapping the candidate genes are followed up at the molecular level by expert animal and human genomics centres. Work packages (5): WP1 - Cancer; WP2 - Cardiovascular Disorders; WP3 - Inflammatory Disorders; WP4 - Neurological Disorders; WP5 - Monogenic Diseases.

Financing

Available with paid subscription only.

Members

Members in 12 countries
More detailed data available with paid subscription.

Type I Classification

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Type II Classification

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Subjects *

  • Biosciences
    • Genetics
  • Birds, Mammals
    • Carnivores
  • Medicine
    • Pathology

UN Sustainable Development Goals **

UIA Org ID

J1911

Last News Received

2012
* Subject classification is derived from the organization names and aims.
** UN SDGs are linked to the subject classification.

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